Cloudy Effluent
In PD patients, mantle cell lymphoma can cause cloudy peritoneal effluent with increased malignant cell count leading to difficulties in the distinction between noninfectious and infectious cloudy dialysate. These difficulties are recurrent and require special attention. The question whether malignancies causing the appearance of atypical cells
PD patients presenting with cloudy effluent should be presumed to have peritonitis and confirmed by obtaining effluent cell count gt 100 WBCmL, differential count, culture and Gram staining72-74. Peritonitis should always be included in the differential diagnosis of any PD patient with abdominal pain, even if the effluent is clear, as a small
However, not all instances of cloudy dialysate are due to infection. This paper will review the various non-infectious causes of cloudy dialysate fluid. Methods Literature review and synthesis. Results Cloudy dialysate may be due to pathologic increases of either cellular or non-cellular constituents of peritoneal fluid. Polymorphonuclear
The first episode of cloudy dialysate was treated for peritonitis. However, the culture of the peritoneal fluid was negative and the mononuclear cells were proven to be atypical lymphocytes of the mantle cell lymphoma variety. In addition to the peritoneal effluent, atypical lymphocytes were also found consistently in the patient's blood
Cloudy effluent is an important clinical finding in patients undergoing peritoneal dialysis and most commonly represents infection or peritonitis However, there are some lesser known causes including certain drugs. Introduction Continuous ambulatory peritoneal dialysis CAPD is an effective treatment modality for patients
Cloudy effluent is a key factor in the detection of peritonitis. This is emphasized in training programs, where patients are instructed to report turbid dialysate immediately. In the hospital, effluent bags are examined for leukocytes. After taking samples for dialysate cultures, antibiotic treatment must be started immediately and should cover
RUST PD Effluent If a patient on PD receives rifampicin and IV iron together, the effluent from the antibiotic-iron combination turns a rusty shade of orange-red.This is a harmless side effect. BRIGHT YELLOW PD Effluent Liver failure, some cancers, or heart failure can cause extra free fluid to build up in the abdomen. This can be very uncomfortable, depending on how much fluid is produced.
However, an occasional patient presents with culture-negative, cloudy dialysate. After ruling out atypical infectious etiologies, a diverse set of aseptic causes remains in the differential diagnosis. Herein we review these causes and suggest an organizational scheme, based on identifying the cellular or noncellular constituent producing the
The most common cause of cloudy effluent is culture positive infectious peritonitis, but the differential dialgnosis includes the following culture negative infectious peritonitis, eosinophilia of the effluent, chemical peritonitis, hemoperitoneum, chylous effluent, malignancy, or a specimen taken from a dry abdomen.
Cloudy effluent usually represents infectious peritonitis, but there could be differential diagnoses aside from infectious peritonitis, such as chemical peritonitis which is a possible side effect of calcium channel blockers, eosinophilia of the effluent, hemoperitoneum, malignancy, chylous effluent, or specimen taken from a dry abdomen.